(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid,(2S)-2-aminopentanedioic acid,(2S)-2-aminopropanoic acid,(2S)-2,6-diaminohexanoic acid
(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid,(2S)-2-aminopentanedioic acid,(2S)-2-aminopropanoic acid,(2S)-2,6-diaminohexanoic acid structure
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Common Name | (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid,(2S)-2-aminopentanedioic acid,(2S)-2-aminopropanoic acid,(2S)-2,6-diaminohexanoic acid | ||
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| CAS Number | 28704-27-0 | Molecular Weight | 563.59900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H41N5O11 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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The development of Cop 1 (Copaxone), an innovative drug for the treatment of multiple sclerosis: personal reflections.
Immunol. Lett. 50(1-2) , 1-15, (1996)
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Dichotomy between the T and the B cell epitopes of the synthetic polypeptide (T,G)-A--L.
Eur. J. Immunol. 24(10) , 2497-505, (1994) Studies with the well-characterized, synthetic, random-multichain polypeptide poly(LTyr,LGlu)-poly(DLAla)-poly(LLys) (T,G)-A-L) led to the discovery of determinant-specific genetic control of the immune response, as well as to other immunological phenomena. M... |
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A coronary artery fistula with saccular aneurysm mimicking a right atrial cystic mass.
Jpn. Heart J. 45(4) , 697-702, (2004) A 16 year-old Korean girl with cardiomegaly was found to have a "right atrial cystic mass" on transthoracic echocardiography. An unusual cystic structure made the diagnosis difficult. However, transesophageal echocardiography and multidetector computed tomogr... |
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Dominant epitopes and synthetic peptides in myasthenia gravis.
Isr. J. Med. Sci. 31(1) , 10-2, (1995)
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Somatic mutation in the neonatal mouse.
J. Immunol. 161(11) , 6093-104, (1998) Several mechanisms that diversify the adult immune repertoire, such as terminal deoxynucleotidyl transferase-dependent N region addition, are not available to the neonatal mouse. One important process that contributes to protective immunity in the adult is so... |
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A peptide sequence mimics the epitope on the multideterminant antigen (Tyr,Glu)-Ala-Lys that induces the dominant H10/V kappa 1+ primary antibody response.
J. Immunol. 152(1) , 136-45, (1994) The multideterminant Ag (Tyr,Glu)-Ala-Lys [(T,G)-A-L] elicits a heterogeneous secondary antibody response to different epitopes consisting of side-chain or backbone residues. However, the primary response is restricted and dominated by side-chain specific ant... |
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Synthesis, structure and function of poly-alpha-amino acids--the simplest of protein models.
Cell. Mol. Life Sci. 53(10) , 780-9, (1997) During the 1950s, linear and multichain poly-alpha-amino acids were synthesized by polymerization of the corresponding N-carboxyamino acid anhydrides in solution in the presence of suitable catalysts. The resulting homo- and heteropolymers have since been wid... |
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Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease.
Immunol. Lett. 58(2) , 79-87, (1997) Graft-versus-host disease (GVHD), which occurs when donor T-cells recognize multiple minor host histocompatibility antigens as non-self, presents the major limitation to successful allogeneic bone-marrow transplantation. The synthetic random copolymer of the ... |
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Effect of macrophage infection by Leishmania on the proliferation of an antigen-specific T-cell line, TPB1, to a non-parasite antigen.
Parasite Immunol. 15(8) , 489-92, (1993) The ability of Leishmania mexicana amazonensis to inhibit antigen specific T-cell proliferation against a non-parasite polypeptide antigen, poly(LTyr, LGlu)-poly(DLAla)--poly(LLys), was examined. Infection of mouse peritoneal macrophages by promastigotes bloc... |
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Structural components responsible for peptide antigenicity.
Appl. Biochem. Biotechnol. 83(1-3) , 63-70; discussion 145-53, (2000) The conformation of a peptide defines its antigenic specificity. In most cases, a free peptide is in a random form, whereas the same peptide within a protein has a defined conformation. Immunological cross-reactions between the two are rare. Nevertheless, the... |