1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine

1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine Structure
1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine structure
Common Name 1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine
CAS Number 19420-56-5 Molecular Weight 521.66700
Density N/A Boiling Point N/A
Molecular Formula C26H52NO7P Melting Point N/A
MSDS USA Flash Point N/A

Polyoxometalates--potent and selective ecto-nucleotidase inhibitors.

Biochem. Pharmacol. 93(2) , 171-81, (2015)

Polyoxometalates (POMs) are inorganic cluster metal complexes that possess versatile biological activities, including antibacterial, anticancer, antidiabetic, and antiviral effects. Their mechanisms of action at the molecular level are largely unknown. Howeve...

Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway.

Invest. Ophthalmol. Vis. Sci. 55(10) , 6187-93, (2014)

We determined bioactivity of lysophospholipids generated by degradation of the low-density (LDL), very low-density (VLDL), and high-density (HDL) lipoproteins with hepatic lipase (HL), cholesterol esterase (CE), and lipoprotein-associated phospholipase A2 (Lp...

Characterization of lysophospholipid metabolizing enzymes in human brain.

J. Neurochem. 63 , 1839-1848, (1994)

Lysophospholipids are generated during the turnover and breakdown of membrane phospholipids. We have identified and partially characterized three enzymes involved in the metabolism of lysophospholipids in human brain, namely, lysophospholipase, lysophospholip...

Molecular identification of lyso-glycerophosphocholines as endogenous immunosuppressives in bovine and rat gonadal fluids.

Biol. Reprod. 79 , 525-536, (2008)

The ability of the gametes to escape detection by the immune system is vital to successful human reproduction. Furthermore, the observed capacity of the testis in some species to support tissue grafts without rejection (immunological privilege) indicates that...

Metabolism and atherogenic disease association of lysophosphatidylcholine.

Atherosclerosis 208 , 10-18, (2010)

Lysophosphatidylcholine (LPC) is a major plasma lipid that has been recognized as an important cell signalling molecule produced under physiological conditions by the action of phospholipase A(2) on phosphatidylcholine. LPC transports glycerophospholipid comp...

Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells.

Atherosclerosis 214 , 338-344, (2011)

Previously we identified palmitoyl-lysophosphatidylcholine (LPC 16:0), as well as linoleoyl-, arachidonoyl- and oleoyl-LPC (LPC 18:2, 20:4 and 18:1) as the most prominent LPC species generated by the action of endothelial lipase (EL) on high-density lipoprote...

Serum biomarkers predictive of pre-eclampsia.

Biomark. Med. 9 , 563-75, (2015)

We sought serum biomarkers predictive of pre-eclampsia (PE).Sera obtained at 12-14 weeks of pregnancy from 24 cases who later developed PE and 24 controls with uncomplicated pregnancies were processed and analyzed using a serum proteomic approach.Many statist...