Aceglutamide

Aceglutamide Structure
Aceglutamide structure
Common Name Aceglutamide
CAS Number 2490-97-3 Molecular Weight 188.181
Density 1.4±0.1 g/cm3 Boiling Point 419.0±55.0 °C at 760 mmHg
Molecular Formula C7H12N2O4 Melting Point 206-208 °C
MSDS Chinese USA Flash Point 207.2±31.5 °C

Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine.

J. Chromatogr. B, Biomed. Appl. 657(1) , 15-21, (1994)

Liquid chromatography-atmospheric pressure chemical-ionization mass spectrometry (LC-APCI-MS) was used for the analysis of N-acetylamino acids that could not be determined with an amino acid analyzer. LC-APCI-MS could directly detect the protonated molecular ...

Availability of glutamine from peptides and acetylglutamine for human tumor-cell cultures.

Metab. Clin. Exp. 38(8 Suppl 1) , 40-2, (1989)

In a recent study we showed that the growth behavior of a hematopoietic cell line (K 562) in culture was the same when using glutamine-containing dipeptides or glutamine as substrate. In this article we study the growth behavior of different tumor cells, orig...

Understanding carbamoyl-phosphate synthetase I (CPS1) deficiency by using expression studies and structure-based analysis.

Hum. Mutat. 31(7) , 801-8, (2010)

Carbamoyl-phosphate synthetase I (CPS1) deficiency (CPS1D), a recessively inherited urea cycle error due to CPS1 gene mutations, causes life-threatening hyperammonemia. The disease-causing potential of missense mutations in CPS1 deficiency can be ascertained ...

NMR and MS analysis of decomposition compounds produced from N-acetyl-L-glutamine at low pH.

J. Agric. Food Chem. 48 , 6003-6010, (2000)

N-Acetyl-L-glutamine decomposition products glutamine, glutamic acid, pyroglutamic acid, N-acetylglutamic acid, and a novel compound, N-(2,6-dioxo-3-piperidinyl) acetamide, have been identified by NMR and MS techniques. N-Acetylglutamine, a modified amino aci...

Absorption of enterally administered N-acetyl-l-glutamine versus glutamine in pigs.

Clin. Nutr. 23 , 1303-1312, (2004)

Glutamine instability in liquid media suggests that evaluation of reasonable enteral nutrition sources of glutamine is needed. N-acetyl-l-glutamine offers no instability and no intolerance problems. This research was conducted to study the absorption and appa...

N-acetyl-L-glutamine, a liquid-stable source of glutamine, partially prevents changes in body weight and on intestinal immunity induced by protein energy malnutrition in pigs.

Dig. Dis. Sci. 52 , 650-658, (2007)

The goal of this study was to evaluate the preventive effect of free glutamine versus N-acetyl-L-glutamine, a liquid-stable source of glutamine, on gut damage induced by protein energy malnutrition in pigs. Healthy pigs (n = 6) were fed a liquid formula for 3...

Uptake of doubly-labelled N-acetyl-L-glutamine in rat brain and intestinal mucosa in vivo.

Il Farmaco 36(7) , 347-55, (1981)

N-acetyl functions and acetate detected by nuclear magnetic resonance spectroscopy of urine to detect renal dysfunction following aminoglycoside and/or glycopeptide antibiotic therapy.

Nephron. Exp. Nephrol. 97(4) , p53-7, (2004)

N-acetylneuraminidine (NeuNAc), N-acetylglutamine (GIcNAc) and acetate are metabolites present in normal urine. In patients treated with aminoglycosides and/or glycopeptides, elevation of these metabolites in urine suggests renal tubular injury. NeuNAc, GIcNA...

Is alpha-ketoisocaproyl-glutamine a suitable glutamine precursor to sustain fibroblast growth?

Clin. Nutr. 18(1) , 29-33, (1999)

Glutamine is considered an essential nutrient for cellular growth.To test the suitability of alpha-ketoisocaproyl-Gln (Kic-Gln) as a new glutamine (Gln) precursor to sustain human fibroblast growth.[3H] thymidine uptake into cellular DNA of human fibroblasts....

New form of pseudohypoparathyroidism with abnormal catalytic adenylate cyclase.

Am. J. Physiol. 257(2 Pt 1) , E277-83, (1989)

Patients with pseudohypoparathyroidism type Ia have resistance to multiple hormones because of deficient activity of the stimulatory guanine nucleotide-binding protein (Gs) that couples membrane receptors to activation of adenylate cyclase. However, in a subs...