Diclazuril

Diclazuril Structure
Diclazuril structure
Common Name Diclazuril
CAS Number 101831-37-2 Molecular Weight 407.638
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H9Cl3N4O2 Melting Point 548ºC
MSDS Chinese USA Flash Point N/A

Increased level of Eimeria sensitivity to diclazuril after using a live coccidial vaccine.

Avian Dis. 50(3) , 321-4, (2006)

Anticoccidial vaccine and an anticoccidial drug rotation program were compared to determine which program was more effective in producing coccidia populations sensitive of 1 ppm diclazuril. The study used an anticoccidial drug-sensitivity battery test (AST) t...

Comparison of three adjuvants used to produce polyclonal antibodies to veterinary drugs.

Vet. Immunol. Immunopathol. 122(1-2) , 25-34, (2008)

Two commercially available adjuvants, Gerbu LQ 3000 and Montanide ISA 50V, were assessed as potential replacements for Freund's adjuvant by evaluating their efficacy in the production of polyclonal antibodies to veterinary drugs in rabbits. The aim was to fin...

Determination of diclazuril, toltrazuril and its two metabolites in poultry tissues and eggs by gel permeation chromatography-liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(20) , 1757-63, (2011)

A new procedure has been described for the extraction of diclazuril (DIZ), toltrazuril (TOZ) and its two main metabolites toltrazuril sulphoxide (TZSO) and toltrazuril sulphone (TZS) from poultry tissues and eggs, using gel permeation chromatography (GPC). Th...

[Determination of avermectin, diclazuril, toltrazuril and metabolite residues in pork by high performance liquid chromatography-tandem mass spectrometry].

Se Pu 29(3) , 217-22, (2011)

A method for the determination of avermectin, ivermectin, doramectin, moxidectin, eprinomectin, diclazuril, toltrazuril and its two metabolite residues in pork was developed using QuEChERS method with high performance liquid chromatography-tandem mass spectro...

Lamb eimeriosis: applied treatment protocols in dairy sheep production systems.

Vet. Parasitol. 196(1-2) , 56-63, (2013)

The effect of different treatment protocols using the triazinone compounds diclazuril and toltrazuril on Eimeria oocyst excretion, diarrhoea and weight gain was evaluated in the present study. The protocols were designed in order to best fit to common managem...

Long-term effect of toltrazuril on growth performances of dairy heifers and beef calves exposed to naturalEimeria zuerniiandEimeria bovisinfections

Vet. J. 190(2) , 296-9, (2011)

The long-term effects of a toltrazuril treatment against natural Eimeria bovis and/or Eimeria zuernii infections were investigated in comparison with diclazuril and untreated controls on two dairy (Italian Friesian breed) and two beef (Chianina breed) farms. ...

Control strategies using diclazuril against coccidiosis in goat kids.

Parasitol. Res. 110(6) , 2131-6, (2012)

Coccidiosis is probably the main parasitic disease affecting goat kids around the weaning period, leading to high economic losses in goat production due to deaths and delayed growth rates of infected animals. A total of 101 kids of 2-4 weeks of age, naturally...

Effect of subcutaneously administered diclazuril on the output of Eimeria species oocysts by experimentally infected rabbits.

Vet. Rec. 162(5) , 153-5, (2008)

The effect of subcutaneously injected diclazuril on the output of Eimeria species oocysts was studied in experimentally infected rabbits. Diclazuril was administered either prophylactically at 0.5, 1 or 2 mg/kg bodyweight two days before each rabbit was inocu...

Efficacy of toltrazuril (Baycox 5% suspension) in natural infections with pathogenic Eimeria spp. in housed lambs.

Parasitol. Res. 104(5) , 1157-62, (2009)

A field study was conducted to evaluate the effect of a single oral treatment with 20 mg/kg body weight (BW) of toltrazuril (Baycox 5% suspension)--TOL--in comparison to a single oral treatment with 1 mg/kg BW of diclazuril (Vecoxan suspension orale, 2.5 mg/m...

Study of the comparative efficacy of toltrazuril and diclazuril against ovine coccidiosis in housed lambs.

Parasitol. Res. 105 Suppl 1 , S141-50, (2009)

A blinded, controlled and randomised field study was conducted on a sheep farm with a known history of coccidiosis and a high prevalence mainly of the pathogenic coccidium Eimeria ovinoidalis. The efficacy of treatment with toltrazuril (Baycox 5% suspension) ...