Prilocaine hydrochloride
Prilocaine hydrochloride structure
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Common Name | Prilocaine hydrochloride | ||
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| CAS Number | 1786-81-8 | Molecular Weight | 256.772 | |
| Density | N/A | Boiling Point | 85°C 4mm | |
| Molecular Formula | C13H21ClN2O | Melting Point | 168-170ºC | |
| MSDS | USA | Flash Point | 134.3ºC | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279... |
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Methemoglobinemia induced by lidocaine-prilocaine cream.
Isr. Med. Assoc. J. 16(4) , 250-4, (2014) With growing awareness of the importance of pain control in all procedures, the use of lidocaine-prilocaine cream (EMLA) for all ages is increasing. Lidocaine-prilocaine cream has been implicated as a cause of methemoglobinemia. Diagnostic clues may be oxygen... |
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Comparison of clinical effects of prilocaine, dexamethasone added to prilocaine and levobupivacaine on brachial plexus block.
J. Pak. Med. Assoc. 64(4) , 433-6, (2014) To determine whether the addition of 8 mg dexamethasone to axillary brachial plexus block would prolong the duration of sensory and motor block in patients undergoing hand and forearm surgery.The prospective, randomised, double-blinded study was conducted at ... |
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Improving the local anesthesia experience for our patients.
Dent. Today 33(4) , 120, 122, 124 passim, (2014)
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Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.
Cochrane Database Syst. Rev. 12 , CD009742, (2014) Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage postoperative pain and reduce bleeding and the physiological re... |
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An uncommon side effect in a common procedure: a case report of an adverse reaction to prilocaine during a Bier's block.
N. Z. Med. J. 127(1407) , 75-9, (2014) This case report describes a rare side effect during a Bier's block. During local anaesthetic injection, the patient suffered a sudden onset painful petechial rash localised to the upper limb, distal to the tourniquet, without systemic effect. After deflation... |
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Lidocaine-prilocaine (EMLA(®) ) cream as analgesia in hysteroscopy practice: a prospective, randomized, non-blinded, controlled study.
Acta Obstet. Gynecol. Scand. 92(8) , 978-81, (2013) We investigated the efficacy of 5% lidocaine 25 mg-prilocaine 25 mg/g cream (EMLA(®) ) applied to the uterine cervix for reducing pain during diagnostic or operative hysteroscopy, using a visual analogue scale (VAS) for pain in a prospective randomized, non-b... |
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An alternative local anaesthesia technique to reduce pain in paediatric patients during needle insertion.
Eur. J. Paediatr. Dent. 14(2) , 109-12, (2013) Pain control, which is necessary during most dental procedures, is administered by injecting a local anaesthetic. Because the injection itself can be painful, the procedure via which pain is reduced warrants continued investigation. Only a few studies regardi... |
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[Efficient treatment of breakthrough pain in adults: the importance of timing and medication choice].
Rev. Med. Suisse 9(392) , 1360, 1362-5, (2013) Diagnostic or therapeutic procedures can lead to breakthrough pain. Thanks to a wise choice of analgesic medication started in due time, this type of pain can be avoided or decreased. The therapeutic options of this preventive approach are presented according... |