1,3-diacetylbenzene
1,3-diacetylbenzene structure
|
Common Name | 1,3-diacetylbenzene | ||
|---|---|---|---|---|
| CAS Number | 6781-42-6 | Molecular Weight | 162.185 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 280.3±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H10O2 | Melting Point | 28-32 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 108.5±19.6 °C | |
|
Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy.
Toxicol. Appl. Pharmacol. 183(1) , 55-65, (2002) The gamma-diketone analogs 1,2-diacetylbenzene (1,2-DAB) and 2,5-hexanedione (2,5-HD), but not the delta-diketone 1,3-diacetylbenzene (1,3-DAB) or the beta-diketone 2,4-hexanedione, induce neuropathological changes in the rodent central and peripheral nervous... |
|
|
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.
J. Med. Chem. 41(21) , 3948-60, (1998) Various cinnammoyl-based structures were synthesized and tested in enzyme assays as inhibitors of the HIV-1 integrase (IN). The majority of compounds were designed as geometrically or conformationally constrained analogues of caffeic acid phenethyl ester (CAP... |
Journals:
More...