5-Ethynyl-2'-deoxycytidine
5-Ethynyl-2'-deoxycytidine structure
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Common Name | 5-Ethynyl-2'-deoxycytidine | ||
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| CAS Number | 69075-47-4 | Molecular Weight | 251.23900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H13N3O4 | Melting Point | 190 °C(dec.) | |
| MSDS | USA | Flash Point | N/A | |
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5-Ethynyl-2'-deoxycytidine as a new agent for DNA labeling: detection of proliferating cells.
Anal. Biochem. 417 , 112-121, (2011) The labeling of newly synthesized DNA in cells to identify cell proliferation is an important experimental technique. The most accurate methods incorporate [(3)H]thymidine or 5-bromo-2'-deoxyruidine (BrdU) into dividing cells during S phase, which is subseque... |
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Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine.
ChemBioChem. 12 , 2184-2190, (2011) 5-Ethynyl-2'-deoxycytidine triphosphate (EdCTP) was synthesized as a probe to be used in conjunction with fluorescent labeling to facilitate the analysis of the in vivo dynamics of DNA-centered processes (DNA replication, repair and cytosine demethylation). K... |
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Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
J. Immunol. 194(4) , 1819-31, (2015) Herpesviruses are DNA viruses harboring the capacity to establish lifelong latent-recurrent infections. There is limited knowledge about viruses targeting the innate DNA-sensing pathway, as well as how the innate system impacts on the latent reservoir of herp... |