Vindesine sulfate

Vindesine sulfate Structure
Vindesine sulfate structure
Common Name Vindesine sulfate
CAS Number 59917-39-4 Molecular Weight 852.00
Density 1.41 g/cm3 Boiling Point N/A
Molecular Formula C43H57N5O11S Melting Point >250ºC
MSDS N/A Flash Point N/A

Validated HILIC-MS/MS assay for determination of vindesine in human plasma: Application to a population pharmacokinetic study

J. Pharm. Biomed. Anal. 96 , 31-6, (2014)

Mean plasma concentration–time profiles of intravenous injection of 3mg Vindesine Sulfate for Injection to 100 unrelated Chinese Han subjects with hematological malignant disorders.

Young patients with non-germinal center B-cell-like diffuse large B-cell lymphoma benefit from intensified chemotherapy with ACVBP plus rituximab compared with CHOP plus rituximab: analysis of data from the Groupe d'Etudes des Lymphomes de l'Adulte/lymphoma study association phase III trial LNH 03-2B.

J. Clin. Oncol. 32(35) , 3996-4003, (2014)

To determine whether any tumor biomarkers could account for the survival advantage observed in the LNH 03-2B trial among patients with diffuse large B-cell lymphoma (DLBCL) and low-intermediate risk according to the International Prognostic Index when treated...

Reovirus cell entry requires functional microtubules.

MBio 4 , (2013)

Mammalian reovirus binds to cell-surface glycans and junctional adhesion molecule A and enters cells by receptor-mediated endocytosis in a process dependent on β1 integrin. Within the endocytic compartment, reovirus undergoes stepwise disassembly, allowing re...

Pharmacology, clinical efficacy and adverse effects of vindesine sulfate, a new vinca alkaloid.

Pharmacotherapy 3(5) , 259-74, (1983)

Vindesine is a new vinca alkaloid antineoplastic agent derived from vinblastine. However, its antineoplastic spectrum more closely resembles that of vincristine. Clinical studies indicate activity against acute leukemia, lung cancer, carcinoma of the breast, ...