L-Arginine hydrochloride

L-Arginine hydrochloride Structure
L-Arginine hydrochloride structure
Common Name L-Arginine hydrochloride
CAS Number 1119-34-2 Molecular Weight 210.662
Density 1.42 Boiling Point 409.1ºC at 760 mmHg
Molecular Formula C6H15ClN4O2 Melting Point 226-230 °C(lit.)
MSDS Chinese USA Flash Point 201.2ºC

Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer.

Biotechnol. Bioeng. 111(8) , 1595-603, (2014)

In this work, a proof of concept elastin-like polypeptide-Z domain fusion (ELP-Z) based affinity precipitation process is developed for monoclonal antibody (mAb) purification from industrial harvest feeds. Greater than 99% mAb recoveries are obtained during t...

Combinatorial effects of arginine and fluoride on oral bacteria.

J. Dent. Res. 94(2) , 344-53, (2015)

Dental caries is closely associated with the microbial disequilibrium between acidogenic/aciduric pathogens and alkali-generating commensal residents within the dental plaque. Fluoride is a widely used anticaries agent, which promotes tooth hard-tissue remine...

Evaluation of miR-216a and miR-217 as potential biomarkers of acute pancreatic injury in rats and mice.

Biomarkers 19(6) , 517-29, (2014)

Mild injury of the exocrine pancreas is often asymptomatic and can be under- or mis-diagnosed. The pancreas-enriched microRNAs miR-216a and miR-217 were evaluated as potential serum biomarkers of exocrine pancreas injury in rodent models of acute pancreatitis...

Suppression of problematic compound oligomerization by cosolubilization of nondetergent sulfobetaines.

ChemMedChem 10(4) , 736-41, (2015)

Numerous small organic compounds exist in equilibrium among monomers, soluble oligomers, and insoluble aggregates in aqueous solution. Compound aggregation is a major reason for false positives in drug screening, and even soluble oligomers can interfere with ...

Exploring advantages/disadvantages and improvements in overcoming gene delivery barriers of amino acid modified trimethylated chitosan.

Pharm. Res. 32 , 2038-50, (2015)

Present study aimed at exploring advantages/disadvantages of amino acid modified trimethylated chitosan in conquering multiple gene delivery obstacles and thus providing comprehensive understandings for improved transfection efficiency.Arginine, cysteine, and...

Enhanced multiparametric hyaluronan degradation for production of molar-mass-defined fragments.

Carbohydr. Polym. 112 , 271-6, (2014)

Hyaluronic acid (HA) is known to serve as a dynamic mediator intervening in many physiological functions. Its specific effect has been repeatedly confirmed to be strongly influenced by the molecular size of hyaluronan fragments. However common technological a...

Evaluation of etanercept degradation under oxidative stress and potential protective effects of various amino acids.

Int. J. Pharm. 492 , 127-36, (2015)

To evaluate the oxidative stability of proteins, a model protein, etanercept, was exposed to oxidative stress conditions using hydrogen peroxide. Various amino acids were also evaluated on their antioxidant effect. Transition temperature (Tm), secondary struc...

Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders.

Amino Acids 47 , 2647-58, (2015)

Cationic amino acid transporters (CATs) mediate the entry of L-type cationic amino acids (arginine, ornithine and lysine) into the cells including neurons. CAT-3, encoded by the SLC7A3 gene on chromosome X, is one of the three CATs present in the human genome...

Combined Aliskiren and L-arginine treatment reverses renovascular hypertension in an animal model.

Hypertens. Res. 38 , 471-7, (2015)

Renovascular hypertension is characterized by increased renal sympathetic activity, angiotensin II and by endothelial dysfunction. The purpose of this study was to determine the role of renal sympathetic nerve activity (RSNA) in mediating the anti-hypertensiv...

Antiproliferative activity of cardenolide glycosides from Asclepias subulata.

J. Ethnopharmacol. 171 , 280-6, (2015)

Asclepias subulata Decne. is a shrub occurring in Sonora-Arizona desert (Mexico-USA). The ethnic groups, Seris and Pimas, use this plant for the treatment of sore eyes, gastrointestinal disorders and cancer.To isolate the compounds responsible for antiprolife...