NQDI 1

NQDI 1 Structure
NQDI 1 structure
Common Name NQDI 1
CAS Number 175026-96-7 Molecular Weight 319.311
Density 1.4±0.1 g/cm3 Boiling Point 581.4±50.0 °C at 760 mmHg
Molecular Formula C19H13NO4 Melting Point N/A
MSDS Chinese USA Flash Point 305.4±30.1 °C

S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3β.

Exp. Cell Res. 318(20) , 2592-603, (2012)

Inflammatory mediators including inducible nitric oxide (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α) and Interleukin-6 (IL-6) contribute to the course of a variety of inflammatory diseases. S632A3 is a new member of the glutarimide antibi...

An ASK1-p38 signalling pathway mediates hydrogen peroxide-induced toxicity in NG108-15 neuronal cells.

Neurosci. Lett. 549 , 163-7, (2013)

Reactive oxygen species (ROS) are believed to be involved in many forms of neurodegeneration, including ischaemic infarct damage and Alzheimer's disease. Despite the known involvement of p38 and JNK MAP kinases in mediating apoptosis and cell death in a varie...