tert-Butyl carbamate
tert-Butyl carbamate structure
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Common Name | tert-Butyl carbamate | ||
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| CAS Number | 4248-19-5 | Molecular Weight | 117.146 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 196.0±9.0 °C at 760 mmHg | |
| Molecular Formula | C5H11NO2 | Melting Point | 105-108 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 82.4±15.0 °C | |
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One-Pot Three-Component Synthesis of Tetrasubstituted NH Pyrroles from Secondary Propargylic Alcohols, 1, 3-Dicarbonyl Compounds and tert-Butyl Carbamate. Cadierno V, et al.
J. Heterocycl. Chem. 47(1) , 233-36, (2010)
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Pd-catalyzed amidation of aryl (Het) halides with< i> tert</i>-butyl carbamate. Qin L, et al.
Tetrahedron Lett. 51(33) , 4446-48, (2010)
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Room-temperature Pd-catalyzed amidation of aryl bromides using tert-butyl carbamate.
J. Org. Chem. 74(12) , 4634-7, (2009) The scope of Pd-catalyzed synthesis of N-Boc-protected anilines from aryl bromides and commercially available tert-butyl carbamate is described. For the first time, this process can be conducted at room temperature (17-22 degrees C) using a combination of Pd(... |
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Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease.
PLoS ONE 7 , e32293, (2012) We describe molecular processes that can facilitate pathogenesis of Alzheimer's disease (AD) by analyzing the catalytic cycle of a membrane-imbedded protease γ-secretase, from the initial interaction with its C99 substrate to the final release of toxic Aβ pep... |