H-Aib-OMe.HCl

H-Aib-OMe.HCl Structure
H-Aib-OMe.HCl structure
Common Name H-Aib-OMe.HCl
CAS Number 15028-41-8 Molecular Weight 153.61
Density N/A Boiling Point 120.6ºC at 760mmHg
Molecular Formula C5H12ClNO2 Melting Point 185°C
MSDS Chinese USA Flash Point 56.1ºC

An efficient and expedient method for the synthesis of 11C-labeled α-aminoisobutyric acid: a tumor imaging agent potentially useful for cancer diagnosis.

Bioorg. Med. Chem. Lett. 21 , 2437-2440, (2011)

We describe the synthesis of (11)C-labeled α-aminoisobutyric acid 2 from iodo[(11)C]methane and methyl N-(diphenylmethylen)-d,l-alaniate (5). The tetrabutylammonium fluoride (TBAF)-promoted α-[(11)C]methylation of sterically hindered analog 5 was a key step i...

Peptide sweeteners. 6. Structural studies on the C-terminal amino acid of L-aspartyl dipeptide sweeteners.

J. Med. Chem. 27 , 1663-1668, (1984)

Stereochemical and structural aspects of the variations in the C-terminal residue of L-aspartyl-L-phenylalanine methyl ester have been investigated. Novel configurational analogues such as L-aspartyl-D-alanine benzyl ester and L-aspartyl-D-alpha-aminobutyric ...

Characterization of glycine transport in cultured Müller glial cells from the retina.

Glia 26 , 273-279, (1999)

Rapid termination of the synaptic action of glutamate (Glu) and glycine (Gly) is achieved by uptake into the presynaptic terminal and glial cells. In the vertebrate CNS, Gly acts both as an inhibitory neurotransmitter and as a Glu modulator or coagonist at po...

Effects of exogenous excitatory amino acid neurotransmitters on blood-brain barrier disruption in focal cerebral ischemia.

Neurochem. Res. 34 , 1249-1254, (2009)

This study was performed to determine whether exogenous N-methyl-D: -aspartate (NMDA) or alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) would aggravate blood-brain barrier (BBB) disruption in focal cerebral ischemia in rats. Forty-five minut...