benzo[b]naphtho[1,2-d]thiophene

benzo[b]naphtho[1,2-d]thiophene Structure
benzo[b]naphtho[1,2-d]thiophene structure
Common Name benzo[b]naphtho[1,2-d]thiophene
CAS Number 205-43-6 Molecular Weight 234.316
Density 1.3±0.1 g/cm3 Boiling Point 434.3±14.0 °C at 760 mmHg
Molecular Formula C16H10S Melting Point 185℃ (acetic acid )
MSDS N/A Flash Point 163.0±6.3 °C

The predominant role of S-oxidation in rat liver metabolism of thiaarenes.

Cancer Lett. 32(1) , 107-16, (1986)

Thiaarenes are metabolized by liver microsomes of untreated rats predominantly to sulfones and sulfoxides. After pretreatment of rats with monooxygenase inducers, ring oxidation of thiaarenes is also observed. In case of benzo[b]naphtho[2,3-d]thiophene the fo...

Towards β-selectivity in functional estrogen receptor antagonists.

Org. Biomol. Chem. 10(36) , 7334-46, (2012)

Based on the benzo[b]naphtho[1,2-d]furan and benzo[b]naphtho[1,2-d]thiophene frameworks, a series of ligands with different basic side chains (BSCs) has been synthesized and pharmacologically evaluated. Also, their binding modes have been modelled using docki...