Diethyl 2-propylmalonate
Diethyl 2-propylmalonate structure
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Common Name | Diethyl 2-propylmalonate | ||
|---|---|---|---|---|
| CAS Number | 2163-48-6 | Molecular Weight | 202.247 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 221.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H18O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 91.7±0.0 °C | |
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Controlled Endolysosomal Release of Agents by pH-responsive Polymer Blend Particles.
Pharm. Res. 32 , 2280-91, (2015) A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cellular functions. In this study, we examined the intracellula... |
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Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.
ACS Nano 9 , 5893-907, (2015) A platform technology has been developed and tested for delivery of intracellular-acting peptides through electrostatically complexed nanoparticles, or nano-polyplexes, formulated from an anionic endosomolytic polymer and cationic therapeutic peptides. This d... |
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Rational design of composition and activity correlations for pH-responsive and glutathione-reactive polymer therapeutics.
J. Control. Release 104(2) , 417-27, (2005) Limited cytoplasmic delivery of enzyme-susceptible drugs remains a significant challenge facing the development of protein and nucleic acid therapies that act in intracellular compartments. "Smart" pH-responsive, membrane-destabilizing polymers present a new ... |