e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Turkish Journal of Chemistry

Friedel-Crafts acylation of arenes with carboxylic acids using silica gel supported AlCl_3

K PARVANAK

Index: Parvanak Boroujeni, Kaveh Turkish Journal of Chemistry, 2010 , vol. 34, # 4 p. 621 - 630

Full Text: HTML

Citation Number: 6

Abstract

Abstract: Aromatic compounds react smoothly with carboxylic acids in the presence of silica gel supported aluminium trichloride to afford the corresponding ketones with high regioselectivity in high to excellent yields. The catalyst is stable (as a bench top catalyst) and

Anthracene Structure

benzoic acid Structure

~89%

Methanone,9-anthracenylphenyl- Structure

Methanone,9-ant...

Anthracene Structure

acetic acid Structure

~87%

9-Acetoanthracene Structure

9-Acetoanthracene

Lauric acid Structure

Toluene Structure

~89%

1-(4-methylphenyl)dodecan-1-one Structure

1-(4-methylphen...

n-heptanoic acid Structure

n-heptanoic acid

Anisole Structure

~89%

1-(4-methoxyphenyl)heptan-1-one Structure

1-(4-methoxyphe...

Chlorobenzene Structure

benzoic acid Structure

~89%

4-Chlorobenzophenone Structure

4-Chlorobenzophenone

4-Methylbenzoic acid Structure

4-Methylbenzoic acid

Toluene Structure

~88%

p-Tolyl ketone Structure

Thiophene(SIV) Structure

4-Nitrobenzoic acid Structure

4-Nitrobenzoic acid

~92%

2-(4-nitrobenzoyl)thiophene Structure

2-(4-nitrobenzo...

Octanoic acid Structure

Toluene Structure

~92%

1-(4-methylphenyl)octan-1-one Structure

1-(4-methylphen...

Toluene Structure

Butyric Acid Structure

~95%

p-Methylbutyrophenone Structure

p-Methylbutyrop...

A highly active ytterbium (iii) methide complex for truly ca...

[Barrett, Anthony G. M.; Bouloc, Nathalie; Braddock, D. Christopher; Chadwick, David; Henderson, David A. Synlett, 2002 , # 10 p. 1653 - 1656]