Tetrahedron

Aerobic oxidation of secondary benzylic alcohols and direct oxidative amidation of aryl aldehydes promoted by sodium hydride

X Wang, DZ Wang

Index: Wang, Xinbo; Wang, David Zhigang Tetrahedron, 2011 , vol. 67, # 19 p. 3406 - 3411

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Citation Number: 49

Abstract

Abstract We reported herein new reactivities and possible mechanistic implications of a simplest oxidant (NaH/air) uncovered on a broad range of useful transformations, including aerobic alcohol oxidations, allylic alcohol isomerizations and oxidations, cyclopropyl alcohol fragmentations, and direct aryl aldehyde oxidative amidations. These readily implementable transition-metal-free processes feature exceptional material accessibility, operational ...