The Journal of Organic Chemistry

Method for transfer of labeled methyl groups

CA Townsend, AB Theis

Index: Townsend, Craig A.; Theis, Alan B. Journal of Organic Chemistry, 1980 , vol. 45, # 9 p. 1697 - 1699

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Citation Number: 7

Abstract

Since their inception a decade ago, lP2 the use of chiral methyl groups has become an established tool of bioorganic investigation. Generation of chiral methyl groups on biotransformation of an appropriately labeled substrate to product followed by excision, typically by Kuhn-Roth oxidation, of the labeled groups as acetic acid and determination of their absolute configuration by established methodology1g2 has allowed the ...