The Journal of Organic Chemistry

Palladium-catalyzed conjugate addition reaction of aryl iodides with. alpha.,. beta.-unsaturated ketones

S Cacchi, A Arcadi

Index: Cacchi, S.; Arcadi, A. Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4236 - 4240

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Citation Number: 74

Abstract

Aryl iodides have been found to react with a $-unsaturated ketones in the presence of catalytic amounts of palladium, an excess of formic acid, and triethylamine, giving rise to conjugate addition type products. The electron-withdrawing power of the group attached to the olefinic double bond, the substituent p to the carbonyl group, and the basic reaction medium appear to affect greatly the conjugate addition/vinylic substitution ratio.