Catalytic Chemical Amide Synthesis at Room Temperature: One More Step Toward Peptide Synthesis

T Mohy El Dine, W Erb, Y Berhault…

Index: Pintori, Didier G.; Greaney, Michael F. Organic Letters, 2011 , vol. 13, # 21 p. 5713 - 5715

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Citation Number: 7

Abstract

... Among the fundamental chemical transformations of organic chemistry, amide synthesis is truly one the most useful, encompassing a wide range of ... acid, Pd(PPh 3 ) 4 (5 mol %), Na 2 CO 3 , DME/EtOH/H 2 O, 90 °C; (f) Furan, n-BuLi ... sieves (1 g), dry fluorobenzene, 65 °C, 24 h. ...