European Journal of Organic Chemistry

Acrolein Diethyl Acetal: A Three??Carbon Homologating Reagent for the Synthesis of β??Arylpropanoates and Cinnamaldehydes by Heck Reaction Catalyzed by a …

E Alacid, C Najera

Index: Alacid, Emilio; Najera, Carmen European Journal of Organic Chemistry, 2008 , # 18 p. 3102 - 3106

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Citation Number: 18

Abstract

Abstract A polymer palladacycle derived from Kaiser oxime resin was used as a source of palladium (0) in the chemoselective Heck reaction of acrolein diethyl acetal with aryl halides under ligand-free conditions. The use of typical Heck conditions afforded 3-arylpropionic esters, and the process can be directed to the synthesis of cinnamaldehydes under Cacchi conditions. These processes take place with rather low loading of the catalyst, which can ...