A simple and efficient procedure for the Beckmann rearrangement of oxime using bis-(trichloromethyl) carbonate/DMF

WK Su, Y Zhang, JJ Li, P Li

Index: Su; Zhang; Li Organic Preparations and Procedures International, 2008 , vol. 40, # 6 p. 543 - 550

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Citation Number: 11

Abstract

Various reaction conditions were investigated and the results are summarized in Table 1. To determine the most appropriate solvent, the reaction was examined using toluene, CH, CI,, CHCI,, THF, CH, CN and DMF; CH, CN was the best solvent (Table 1, Entry 6) in terms of yields. As shown in Table 1, it was also found that the reaction was facilitated by increasing the