Acetamide,N,N'-1,3-phenylenebis-

Modify Date: 2025-08-25 14:27:50

Acetamide,N,N'-1,3-phenylenebis- Structure
Acetamide,N,N'-1,3-phenylenebis- structure
 Common Name Acetamide,N,N'-1,3-phenylenebis-
CAS Number 10268-78-7 Molecular Weight 192.21400
Density 1.235g/cm3 Boiling Point 475.2ºC at 760mmHg
Molecular Formula C10H12N2O2 Melting Point N/A
MSDS N/A Flash Point 215.4ºC

 Names

Name N-(3-acetamidophenyl)acetamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.235g/cm3
Boiling Point 475.2ºC at 760mmHg
Molecular Formula C10H12N2O2
Molecular Weight 192.21400
Flash Point 215.4ºC
Exact Mass 192.09000
PSA 58.20000
LogP 1.74940
Vapour Pressure 3.39E-09mmHg at 25°C
Index of Refraction 1.621

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC7709000
CHEMICAL NAME :
Acetamide, N,N'-1,3-phenylenebis-
CAS REGISTRY NUMBER :
10268-78-7
BEILSTEIN REFERENCE NO. :
0910978
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H12-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10700 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(2),42,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(2),42,1991

 Safety Information

HS Code 2924299090

 Synthetic Route

Acetamide structure

Acetamide

CAS#:60-35-5

Acetamide,N-(3-chlorophenyl)- structure

Acetamide,N-(3-...

CAS#:588-07-8

~98%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Ikawa, Takashi; Barder, Timothy E.; Biscoe, Mark R.; Buchwald, Stephen L. Journal of the American Chemical Society, 2007 , vol. 129, # 43 p. 13001 - 13007
Ethanoic anhydride structure

Ethanoic anhydride

CAS#:108-24-7

m-Phenylenediamine structure

m-Phenylenediamine

CAS#:108-45-2

~96%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Chakrabarty; Batabyal; Khasnobis Synthetic Communications, 2000 , vol. 30, # 20 p. 3651 - 3668
1-(3-acetylamino-phenyl)-ethanone oxime structure

1-(3-acetylamin...

CAS#:39569-37-4

~82%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Su; Zhang; Li Organic Preparations and Procedures International, 2008 , vol. 40, # 6 p. 543 - 550
m-Phenylenediamine structure

m-Phenylenediamine

CAS#:108-45-2

Acetyl chloride structure

Acetyl chloride

CAS#:75-36-5

~%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Olson; Feldman Journal of the American Chemical Society, 1937 , vol. 59, p. 2003
Ethanoic anhydride structure

Ethanoic anhydride

CAS#:108-24-7

1,3-diaminobenzene monohydrochloride structure

1,3-diaminobenz...

CAS#:17025-58-0

~%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Phillips Journal of the Chemical Society, 1925 , vol. 128, p. 174
m-Phenylenediamine structure

m-Phenylenediamine

CAS#:108-45-2

acetic acid structure

acetic acid

CAS#:64-19-7

~%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Barbaglia Chemische Berichte, 1874 , vol. 7, p. 1257
Acetamide structure

Acetamide

CAS#:60-35-5

m-Phenylenediamine structure

m-Phenylenediamine

CAS#:108-45-2

~%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Kelbe Chemische Berichte, 1883 , vol. 16, p. 1200
m-Phenylenediamine structure

m-Phenylenediamine

CAS#:108-45-2

~%

Acetamide,N,N'-1,3-phenylenebis- Structure

Acetamide,N,N'-...

CAS#:10268-78-7

Literature: Barbaglia Chemische Berichte, 1874 , vol. 7, p. 1257

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

N,N'-diacetyl-1,3-phenylenediamine
N,N'-1,3-Phenylenebisacetamide
Acetamide,N,N'-1,3-phenylenebis
N,N'-bisacetyl-1,3-phenylenediamine
N,N'-(m-Phenylene)di(acetamide)
1,3-Diacetamidobenzene
m-phenylenediamine N,N'-diacetate
N-(3-acetylamino-phenyl)acetamide
1,3-diacetylaminobenzene
1,3-bis-acetylaminobenzene
1,3-Bisacetamidobenzene
EINECS 233-609-7
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