Tetrahedron

Oxidatively sonochemical dealkylation of various N-alkylsulfonamides to free sulfonamides and aldehydes

M Katohgi, H Togo

Index: Katohgi, Masashi; Togo, Hideo Tetrahedron, 2001 , vol. 57, # 35 p. 7481 - 7486

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Citation Number: 21

Abstract

Various N-alkylsulfonamides were easily dealkylated to give the corresponding free sulfonamides in moderate to good yields in the presence of (diacetoxyiodo) benzene and iodine under ultrasonic irradiation. Application of this methodology to various N-protected alkylamines with sulfonyl, phosphonyl, and acyl groups was carried out, and the oxidative conversion occurred only in N-sulfonyl-protected phenylalkylamines to give the ...