The Journal of Organic Chemistry

Synthesis of phenoxyamines

AJ Castellino, H Rapoport

Index: Castellino, Angelo J.; Rapoport, Henry Journal of Organic Chemistry, 1984 , vol. 49, p. 1348 - 1352

Full Text: HTML

Citation Number: 21

Abstract

Treatment of phenols with 2, 4-dinitrophenoxyamine leads to the synthesis of phenoxyamines through an amine exchange reaction. Yields for this reaction are sensitive to the pK, of the phenol in a manner explainable in terms of a competing bimolecular decomposition reaction involving the 2, 4-dinitrophenoxyamine. By use of an appropriately substituted phenol, this phenomenon can be exploited to give high yields of ...