Monatshefte für Chemie/Chemical Monthly

Über Reaktionen mit Betainen, 23. Mitt. Über Umsetzungen von N-und S-Betainen mit reaktiven Halogenverbindungen

H Wittmann, E Ziegler

Index: Wittmann, Helga; Ziegler, Erich Monatshefte fuer Chemie, 1988 , vol. 119, p. 103 - 112

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Citation Number: 6

Abstract

Abstract Trimethylammonium acetic acid betain (1) reacts with phenacyl bromide and ethyl bromoacetate, respectively, to give the ester bromides 2 and 7. These can be hydrolyzed with aqueous sodium hydrogencarbonate at 20° C to yield besides 1 both C-benzoyl- methanol (3) and the glycolic acid ester 8, respectively. The reaction can also be performed in one step by reacting the betain (1)(which can act as a base) in a double molar ratio with ...