Glycolophenone

Modify Date: 2025-08-23 11:06:44

Glycolophenone Structure
Glycolophenone structure
 Common Name Glycolophenone
CAS Number 582-24-1 Molecular Weight 136.148
Density 1.1±0.1 g/cm3 Boiling Point 244.6±13.0 °C at 760 mmHg
Molecular Formula C8H8O2 Melting Point 86-89 °C(lit.)
MSDS Chinese USA Flash Point 100.4±12.4 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Glycolophenone


2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis[1]. 2-Hydroxyacetophenone shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM[2].

 Names

Name 2-hydroxyacetophenone
Synonym More Synonyms

 Glycolophenone Biological Activity

Description 2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis[1]. 2-Hydroxyacetophenone shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM[2].
Related Catalog
Target

HIV

References

[1]. M D Bentley, et al. 2-Hydroxyacetophenone: principal root volatile of the East African medicinal plant, Carissa edulis. J Nat Prod. Nov-Dec 1984;47(6):1056-7.

[2]. Min Zhuang, et al. Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Antiviral Res. 2009 Apr;82(1):73-81.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 244.6±13.0 °C at 760 mmHg
Melting Point 86-89 °C(lit.)
Molecular Formula C8H8O2
Molecular Weight 136.148
Flash Point 100.4±12.4 °C
Exact Mass 136.052429
PSA 37.30000
LogP 0.44
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.551

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2914400090

 Synthetic Route

 Customs

HS Code 2914400090
Summary 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles5

More Articles
Urinalysis of minor metabolites of ethylbenzene and m-xylene.

Scand. J. Work. Environ. Health 10(2) , 75-81, (1984)

Gas chromatographic methods have been developed for the urinalysis of metabolic products of ethylbenzene. "Minor" metabolites were emphasized in this process. The methods were worked out so that simul...

Synthesis and structural characterization of mixed ligand ? 1-2-hydroxyacetophenone complexes of cobalt (III). Mondal N, et al.

Polyhedron 19(28) , 2707-11, (2000)

Solvent-free microwave-assisted Beckmann rearrangement of benzaldehyde and 2-hydroxyacetophenone oximes. Loupy A and Régnier S.

Tetrahedron Lett. 40(34) , 6221-24, (1999)

 Synonyms

2-Hydroxyacetophenone
MFCD00041829
Glycolophenone
EINECS 209-480-8
Methanol, benzoyl-
Benzoylcarbinol
2-Hydroxy-1-phenylethanone
HYDROXYACETOPHENONE
α-hydroxyacetophenone
Ethanone, 2-hydroxy-1-phenyl-
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