Tetrahedron letters

Synthesis of pyrimidines from ketones using microwave irradiation

S Tyagarajan, PK Chakravarty

Index: Tyagarajan, Sriram; Chakravarty, Prasun K. Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7889 - 7891

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Citation Number: 19

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A simple, high yielding synthesis of pyrimidines from ketones in the presence of HMDS and formamide is described. Under microwave irradiation, heteroaromatic, aryl, aliphatic, and cyclic ketones cyclized to give pyrimidines in good yields. ... Under microwave irradiation, aromatic, ...

~44%

~55%

~65%

~43%

~26%

~18%

~89%

~46%

~82%

~78%

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