Measurement of Postreplicative DNA Metabolism and Damage in the Rodent Brain

JP Patel, ML Sowers, JL Herring…

Index: Miyashita; Matsumura; Shimadzu; Hashimoto Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 11 p. 3181 - 3190

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Citation Number: 0

Abstract

... dependent dioxygenases have been shown to convert 5mC to 5hmC in DNA.(11) Further details of ... DNA bases can also be modified by chemical reactions including both oxidation and deamination.(15 ... The water extracts were combined and concentrated to a volume of 10 mL. ...

 Related Synthetic Route
Triethyl orthoformate Structure

122-51-0

Triethyl orthof...

Urea Structure

57-13-6

Urea

Diethyl malonate Structure

105-53-3

Diethyl malonate

~67%

Propanedioic Acid, 2-[[(Aminocarbonyl)Amino]Methylene]-,1,3-Diethyl Ester Structure

61679-84-3

Propanedioic Ac...

Methyl 5-fluoro-4-methoxy-2,6-dioxohexahydro-5-pyrimidinecarboxylate Structure

65905-96-6

Methyl 5-fluoro...

~92%

Fluorouracil Structure

51-21-8

Fluorouracil

5-fluoro-6-hydroxy-5-methoxycarbonyl-5,6-dihydrouracil Structure

65726-47-8

5-fluoro-6-hydr...

~63%

Fluorouracil Structure

51-21-8

Fluorouracil

sodium isoorotate Structure

3252-17-3

sodium isoorotate

~39%

5-Bromouracil Structure

51-20-7

5-Bromouracil

Uracil Structure

66-22-8

Uracil

~42%

2,4(1H,3H)-Pyrimidinedione,5-fluorodihydro-6-hydroxy- Structure

37103-91-6

2,4(1H,3H)-Pyri...

5-fluoro-1-(2-tetrahydrofuryl)-6-hydroxy-5-methoxycarbonyl-5,6-dihydrouracil Structure

65906-08-3

5-fluoro-1-(2-t...

~82%

Tegafur Structure

17902-23-7

Tegafur

5-chloro-6-hydroxy-5-methoxycarbonyl-5,6-dihydrouracil Structure

65906-87-8

5-chloro-6-hydr...

~26%

5-Chlorouracil Structure

1820-81-1

5-Chlorouracil

2,4-Dihydroxypyrimidine-5-carboxylic acid Structure

23945-44-0

2,4-Dihydroxypy...

~45%

5,5-difluoro-6-hydroxy-1,3-diazinane-2,4-dione Structure

55052-50-1

5,5-difluoro-6-...

Propanedioic Acid, 2-[[(Aminocarbonyl)Amino]Methylene]-,1,3-Diethyl Ester Structure

61679-84-3

Propanedioic Ac...

~71%

5-carbethoxyuracil Structure

28485-17-8

5-carbethoxyuracil

Diethyl malonate Structure

105-53-3

Diethyl malonate

~%

5-carbethoxyuracil Structure

28485-17-8

5-carbethoxyuracil

methyl ureidomethylenemalonate Structure

65696-20-0

methyl ureidome...

~%

Methyl 5-fluoro-4-methoxy-2,6-dioxohexahydro-5-pyrimidinecarboxylate Structure

65905-96-6

Methyl 5-fluoro...

methyl ureidomethylenemalonate Structure

65696-20-0

methyl ureidome...

~%

5-PYRIMIDINECARBOXAMIDE, 1,2,3,4-TETRAHYDRO-2,4-DIOXO- Structure

1074-97-1

5-PYRIMIDINECAR...


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