Organic letters

Copper-Mediated Transformation of Organosilanes to Nitriles with DMF and Ammonium Iodide

Z Wang, S Chang

Index: Wang, Zhen; Chang, Sukbok Organic Letters, 2013 , vol. 15, # 8 p. 1990 - 1993

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Citation Number: 2

Abstract

Cyanation of aryl-, diaryldimethyl-, and styrylsilanes was developed for the first time under copper-mediated oxidative conditions using ammonium iodide and DMF as the combined source of nitrogen and carbon atom of the introduced cyano unit, respectively. The reaction was observed to proceed in a two-step process: initial conversion of organosilanes to their iodo intermediates and then cyanation. This method has a broad substrate scope with ...