Synthetic Communications

Reaction of Diphenacylanilines with 2-Aminobenzophenone: An Abnormal Friedlander Reaction Yielding Indoles

N Paul, S Muthusubramanian

Index: Paul, Nidhin; Muthusubramanian, Shanmugam Synthetic Communications, 2013 , vol. 43, # 8 p. 1200 - 1209

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Abstract

Many of the bioactive alkaloids from the plants of marine or terrestrial domain are based on the indole moiety. [ 1 1. (a) Snieckus , V. In The Alkaloids ; Academic Press : New York , 1968 ; Vol. 11 , pp. 1 – 33 ; (b) Gribble , GW In Comprehensive Heterocyclic Chemistry, , 2nd ed. ; Pergamon Press : New York , 1996 ; Vol. 2 , pp. 203 – 257 ; (c) McCoy , E. ; Galan , MC ; O'Connor , SE Substrate specificity of strictosidine synthase. Bioorg. Med. Chem. Lett. 2006, 16, 2475–2478 ; (d) ...