Unsymmetrical diaryl sulfones and aryl vinyl sulfones through palladium-catalyzed coupling of aryl and vinyl halides or triflates with sulfinic acid salts

S Cacchi, G Fabrizi, A Goggiamani…

Index: Cacchi, Sandro; Fabrizi, Giancarlo; Goggiamani, Antonella; Parisi, Luca M.; Bernini, Roberta Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5608 - 5614

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Citation Number: 143

Abstract

The palladium-catalyzed reaction of sulfinic acid salts with a wide variety of aryl and vinyl halides or triflates provides unsymmetrical diaryl sulfones and aryl vinyl sulfones in good to excellent yields. The reaction is strongly influenced by the presence of n Bu4NCl, and the use of Xantphos, a rigid bidentate ligand with a wide natural bite angle, was found to be crucial for the success of the reaction. With neutral, electron-rich, and electron-poor aryl ...