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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Ring cleavage reaction of 1, 3-oxazine-2, 4 (3H)-dione derivatives with amines.

木下敏夫, 竹内梢, 近藤雅也, 古川淳

Index: Chemical and Pharmaceutical Bulletin, , vol. 37, # 8 p. 2026 - 2029

Full Text: HTML

Citation Number: 6

Abstract

... C1-C6H4 HOCHZCHZ c sec-BuNH dp—Cl—C6H4 n-Bu d CZHSO Chart] 1989 Pharmaceutical Society of ... Chemical shifts are reported in ppm (5) relative to tetramethylsilane (TMS) as an internal standard. ... 68—69; h) M. Sajnsbury, “Comprehensive Heterocyclic Chemistry,” Vol. ...

 Related Synthetic Route
morpholine Structure

110-91-8

morpholine

3-(4-CHLORO-PHENYL)-6-METHYL-[1,3]OXAZINE-2,4-DIONE Structure

30645-78-4

3-(4-CHLORO-PHE...

~59%

1,3-Butanedione,1-(4-morpholinyl) Structure

16695-54-8

1,3-Butanedione...

N-(4-Chlorophenyl)carbamic acid methyl ester Structure

940-36-3

N-(4-Chlorophen...

Learn More
3-(4-CHLORO-PHENYL)-6-METHYL-[1,3]OXAZINE-2,4-DIONE Structure

30645-78-4

3-(4-CHLORO-PHE...

~59%

1,3-Butanedione,1-(4-morpholinyl) Structure

16695-54-8

1,3-Butanedione...

N-(4-Chlorophenyl)carbamic acid methyl ester Structure

940-36-3

N-(4-Chlorophen...

Learn More
morpholine Structure

110-91-8

morpholine

3,6-dimethyl-1,3-oxazine-2,4-dione Structure

10128-60-6

3,6-dimethyl-1,...

~44%

1,3-Butanedione,1-(4-morpholinyl) Structure

16695-54-8

1,3-Butanedione...

4-Morpholinecarboxamide,N-methyl-(9CI) Structure

126401-65-8

4-Morpholinecar...

Learn More
morpholine Structure

110-91-8

morpholine

3-phenyl-3,4-dihydro-6-methyl-2H-1,3-oxazine-2,4-dione Structure

34132-56-4

3-phenyl-3,4-di...

~44%

1,3-Butanedione,1-(4-morpholinyl) Structure

16695-54-8

1,3-Butanedione...

4-Morpholinecarboxamide,N-phenyl Structure

4559-92-6

4-Morpholinecar...

Detail Learn More
3-(4-CHLORO-PHENYL)-6-METHYL-[1,3]OXAZINE-2,4-DIONE Structure

30645-78-4

3-(4-CHLORO-PHE...

~52%

4′-Chloroacetoacetanilide Structure

101-92-8

4′-Chloroacetoa...

Learn More
3-(4-CHLORO-PHENYL)-6-METHYL-[1,3]OXAZINE-2,4-DIONE Structure

30645-78-4

3-(4-CHLORO-PHE...

2-Aminoethanol Structure

141-43-5

2-Aminoethanol

~18%

4′-Chloroacetoacetanilide Structure

101-92-8

4′-Chloroacetoa...

3-(4-Chlorophenyl)-1-(2-hydroxyethyl)-6-methyl-2,4(1H,3H)-pyrimidinedione Structure

126401-63-6

3-(4-Chlorophen...

Learn More
3-phenyl-3,4-dihydro-6-methyl-2H-1,3-oxazine-2,4-dione Structure

34132-56-4

3-phenyl-3,4-di...

~28%

3-Oxo-N-phenylbutanamide Structure

102-01-2

3-Oxo-N-phenylb...

1-(2-hydroxyethyl)-6-methyl-3-phenyl-2,4(1H,3H)-pyrimidinedione Structure

38756-99-9

1-(2-hydroxyeth...

Learn More
3-phenyl-3,4-dihydro-6-methyl-2H-1,3-oxazine-2,4-dione Structure

34132-56-4

3-phenyl-3,4-di...

2-Aminoethanol Structure

141-43-5

2-Aminoethanol

~15%

3-Oxo-N-phenylbutanamide Structure

102-01-2

3-Oxo-N-phenylb...

1-(2-hydroxyethyl)-6-methyl-3-phenyl-2,4(1H,3H)-pyrimidinedione Structure

38756-99-9

1-(2-hydroxyeth...

Learn More
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Detail Synthetic Route


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