benzo-12-crown-4

Modify Date: 2025-08-25 19:43:59

benzo-12-crown-4 Structure
benzo-12-crown-4 structure
Common Name benzo-12-crown-4
CAS Number 14174-08-4 Molecular Weight 224.253
Density 1.1±0.1 g/cm3 Boiling Point 341.8±37.0 °C at 760 mmHg
Molecular Formula C12H16O4 Melting Point 42-45 °C(lit.)
MSDS N/A Flash Point 136.4±33.3 °C

 Names

Name Benzo-12-crown 4-Ether
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 341.8±37.0 °C at 760 mmHg
Melting Point 42-45 °C(lit.)
Molecular Formula C12H16O4
Molecular Weight 224.253
Flash Point 136.4±33.3 °C
Exact Mass 224.104858
PSA 36.92000
LogP 0.78
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.479
InChIKey OAJNZFCPJVBYHB-UHFFFAOYSA-N
SMILES c1ccc2c(c1)OCCOCCOCCO2

 Safety Information

Hazard Codes Xi,Xn
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
WGK Germany 3
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 benzo-12-crown-4Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen
Source: NCGC
External Id: tdp43-p2-repeat
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

BENZO-12-CROWN-4
2,3-Benzo-1,4,7,10-tetraoxadodec-2-ene
2,5,8,11-tetraoxabicyclo[10.4.0]hexadeca-1(16),12,14-triene
2,3,5,6,8,9-Hexahydro-1,4,7,10-benzotetraoxacyclododecine
MFCD00059934
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