3,3'-diiodo-L-thyronine
3,3'-diiodo-L-thyronine structure
|
Common Name | 3,3'-diiodo-L-thyronine | ||
|---|---|---|---|---|
| CAS Number | 4604-41-5 | Molecular Weight | 525.077 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 520.7±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H13I2NO4 | Melting Point | 178-180ºC | |
| MSDS | USA | Flash Point | 268.7±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 3,3'-diiodo-L-thyronine3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3,3'-diiodo-L-thyronine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite COX |
| In Vitro | 3,3'-Diiodo-L-thyronine (3,3'-T2; 1 μM; 30 min) significantly enhances COX activity[2]. 3,3'-Diiodo-L-thyronine of 1 μM has the maximum effect[2]. 3,3'-Diiodo-L-thyronine is produced by further degradation of T3 and rT3[3]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 520.7±50.0 °C at 760 mmHg |
| Melting Point | 178-180ºC |
| Molecular Formula | C15H13I2NO4 |
| Molecular Weight | 525.077 |
| Flash Point | 268.7±30.1 °C |
| Exact Mass | 524.893372 |
| PSA | 92.78000 |
| LogP | 4.55 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.726 |
| InChIKey | CPCJBZABTUOGNM-LBPRGKRZSA-N |
| SMILES | NC(Cc1ccc(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O |
| Storage condition | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Redesigned Escherichia coli cytosine deaminase: a new facet of suicide gene therapy.
J. Gene Med. 17 , 132-9, (2015) The Escherichia coli cytosine deaminase (CD)/5-fluorocytosine (5-FC) approach emerges as a potential aid for suicide gene therapy in the field of modern cancer treatment. However, the poor binding aff... |
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Axial T1ρ MRI as a diagnostic imaging modality to quantify proteoglycan concentration in degenerative disc disease.
Eur. Spine J. 24 , 2395-401, (2015) The aim of the study was to investigate if axial T1ρ MR images had similar accuracy as established sagittal T1ρ MRI for the assessment of proteoglycan concentration and content in intervertebral degen... |
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Spider wrapping silk fibre architecture arising from its modular soluble protein precursor.
Sci. Rep. 5 , 11502, (2015) Spiders store spidroins in their silk glands as high concentration aqueous solutions, spinning these dopes into fibres with outstanding mechanical properties. Aciniform (or wrapping) silk is the tough... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluo...
Source: ChEMBL
Target: Proliferating cell nuclear antigen
External Id: CHEMBL2352795
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3,3’-Diiodo-L-thyronine |
| O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine |
| 3,3'-Diiodo-L-thyronine |
| EINECS 225-005-7 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of 3,3'-diiodo-L-thyronine? |
| A: The English name of 3,3'-diiodo-L-thyronine is 3,3'-diiodo-L-thyronine. |
| Q: What is the polar surface area (PSA) of 3,3'-diiodo-L-thyronine? |
| A: Polar surface area (PSA) of 3,3'-diiodo-L-thyronine is 92.78000. |
| Q: What are the uses of 3,3'-diiodo-L-thyronine? |
| A: Main uses of 3,3'-diiodo-L-thyronine: 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[1][2]. |
| Q: What English synonyms does 3,3'-diiodo-L-thyronine have? |
| A: English synonyms of 3,3'-diiodo-L-thyronine: 3,3’-Diiodo-L-thyronine, O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine, 3,3'-Diiodo-L-thyronine, EINECS 225-005-7. |
| Q: What is the SMILES notation of 3,3'-diiodo-L-thyronine? |
| A: SMILES notation of 3,3'-diiodo-L-thyronine is NC(Cc1ccc(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O. |
| Q: What is the LogP of 3,3'-diiodo-L-thyronine? |
| A: LogP of 3,3'-diiodo-L-thyronine is 4.55. |
| Q: What is the CAS number of 3,3'-diiodo-L-thyronine? |
| A: CAS number of 3,3'-diiodo-L-thyronine is 4604-41-5. |
| Q: What is the molecular formula of 3,3'-diiodo-L-thyronine? |
| A: Molecular formula of 3,3'-diiodo-L-thyronine is C15H13I2NO4. |
| Q: What is the boiling point of 3,3'-diiodo-L-thyronine? |
| A: Boiling point of 3,3'-diiodo-L-thyronine is 520.7±50.0 °C at 760 mmHg. |
| Q: What is the InChIKey of 3,3'-diiodo-L-thyronine? |
| A: InChIKey of 3,3'-diiodo-L-thyronine is CPCJBZABTUOGNM-LBPRGKRZSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |