L-Arginine-d7 hydrochloride

Modify Date: 2024-01-09 08:38:16

L-Arginine-d7 hydrochloride Structure
L-Arginine-d7 hydrochloride structure
Common Name L-Arginine-d7 hydrochloride
CAS Number 204244-77-9 Molecular Weight 217.705
Density N/A Boiling Point N/A
Molecular Formula C6H8D7ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Arginine-d7 hydrochloride


L-Arginine-d7 ((S)-(+)-Arginine-d7) hydrochloride is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

 Names

Name L-Arginine:Hcl (D7)
Synonym More Synonyms

 L-Arginine-d7 hydrochloride Biological Activity

Description L-Arginine-d7 ((S)-(+)-Arginine-d7) hydrochloride is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C6H8D7ClN4O2
Molecular Weight 217.705
Exact Mass 217.132294
Storage condition -20C

 Synonyms

L-(2,3,3,4,4,5,5-2H7)Arginine hydrochloride (1:1)
MFCD00144556
L-Arginine-2,3,3,4,4,5,5-d7, hydrochloride (1:1)