MC-Val-Cit-PAB-Auristatin E

Modify Date: 2024-01-01 23:39:40

MC-Val-Cit-PAB-Auristatin E structure	Common Name	MC-Val-Cit-PAB-Auristatin E
	CAS Number	2055896-77-8	Molecular Weight	1287.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₈H₁₀₈N₁₁O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MC-Val-Cit-PAB-Auristatin E

MC-Val-Cit-PAB-Auristatin E has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-Auristatin E is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].

Name	MC-Val-Cit-PAB-Auristatin E

Description	MC-Val-Cit-PAB-Auristatin E has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-Auristatin E is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
References	[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

Molecular Formula	C₆₈H₁₀₈N₁₁O₁₃
Molecular Weight	1287.65

MC-Val-Cit-PAB-Auristatin E

Use of MC-Val-Cit-PAB-Auristatin E

Names

MC-Val-Cit-PAB-Auristatin E Biological Activity

Chemical & Physical Properties