MC-Val-Cit-PAB-NH-C2-NH-Boc

Modify Date: 2025-08-25 06:43:37

MC-Val-Cit-PAB-NH-C2-NH-Boc Structure
MC-Val-Cit-PAB-NH-C2-NH-Boc structure
Common Name MC-Val-Cit-PAB-NH-C2-NH-Boc
CAS Number 1616727-22-0 Molecular Weight 758.86
Density N/A Boiling Point N/A
Molecular Formula C36H54N8O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Val-Cit-PAB-NH-C2-NH-Boc


MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name MC-Val-Cit-PAB-NH-C2-NH-Boc

 MC-Val-Cit-PAB-NH-C2-NH-Boc Biological Activity

Description MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.

 Chemical & Physical Properties

Molecular Formula C36H54N8O10
Molecular Weight 758.86
InChIKey NBIUDKXQNRHCFG-YZNIXAGQSA-N
SMILES CC(C)C(NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)NCCNC(=O)OC(C)(C)C)cc1
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