Mc-Val-Cit-PAB-Cl

Modify Date: 2024-01-10 19:56:16

Mc-Val-Cit-PAB-Cl structure	Common Name	Mc-Val-Cit-PAB-Cl
	CAS Number	1639351-92-0	Molecular Weight	591.10
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₉ClN₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mc-Val-Cit-PAB-Cl

Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

Name	Mc-Val-Cit-PAB-Cl

Description	Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Alkyl/ether
References	[1]. Staben LR, et al. Stabilizing a Tubulysin Antibody-Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors. ACS Med Chem Lett. 2017 Sep 5;8(10):1037-1041.

Molecular Formula	C₂₈H₃₉ClN₆O₆
Molecular Weight	591.10
Storage condition	-20°C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mc-Val-Cit-PAB-Cl
Price: Click To Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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