Apoptin-derived peptide

Modify Date: 2024-01-08 16:11:47

Apoptin-derived peptide Structure
Apoptin-derived peptide structure
Common Name Apoptin-derived peptide
CAS Number 2232156-31-7 Molecular Weight 5177.33
Density N/A Boiling Point N/A
Molecular Formula C223H417N89O50S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Apoptin-derived peptide


Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide promotes apoptosis and necrosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide inhibited the invasion and migration of cancer cells, and inhibited the expression and phosphorylation of the subunit p85 of PI3K, which further inhibited the PI3K/AKT pathway involved in the development of gastric cancer[1].

 Names

Name Apoptin-derived peptide

 Apoptin-derived peptide Biological Activity

Description Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide promotes apoptosis and necrosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide inhibited the invasion and migration of cancer cells, and inhibited the expression and phosphorylation of the subunit p85 of PI3K, which further inhibited the PI3K/AKT pathway involved in the development of gastric cancer[1].
Related Catalog
References

[1]. Zhou D, et al. Apoptin-derived peptide reverses cisplatin resistance in gastric cancer through the PI3K-AKT signaling pathway [J]. Cancer Medicine, 2018, 7(4): 1369-1383.  

 Chemical & Physical Properties

Molecular Formula C223H417N89O50S
Molecular Weight 5177.33
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