RTS-V5

Modify Date: 2024-01-06 18:15:00

RTS-V5 structure	Common Name	RTS-V5
	CAS Number	2285346-31-6	Molecular Weight	525.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₅N₅O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RTS-V5

RTS-V5 is a dual HDAC/proteasome inhibitor with IC50s of 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively.

Name	RTS-V5

Description	RTS-V5 is a dual HDAC/proteasome inhibitor with IC50s of 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Signaling Pathways >> Epigenetics >> HDAC
Target	IC50: 6.9 nM (HDAC1), 18 nM (HDAC2), 15 nM (HDAC3), 0.27 nM (HDAC6), 0.53 nM (HDAC8)[1]
References	[1]. Bhatia S, et al. Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. J Med Chem. 2018 Nov 21;61(22):10299-10309.

Molecular Formula	C₂₇H₃₅N₅O₆
Molecular Weight	525.60