Tauro-β-muricholic acid
Modify Date: 2024-01-10 08:13:15
Tauro-β-muricholic acid structure
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Common Name | Tauro-β-muricholic acid | ||
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| CAS Number | 25696-60-0 | Molecular Weight | 515.70300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H45NO7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tauro-β-muricholic acidTauro-β-muricholic acid (TβMCA) is a trihydroxylated bile acid. Tauro-β-muricholic acid is a competitive and reversible FXR antagonist (IC50 = 40 μM). Tauro-β-muricholic acid has antiapoptotic effect. Tauro-β-muricholic acid inhibits bile acid-induced hepatocellular apoptosis by maintaining the mitochondrial membrane potential[1][2]. |
| Name | tauroβ-muricholic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Tauro-β-muricholic acid (TβMCA) is a trihydroxylated bile acid. Tauro-β-muricholic acid is a competitive and reversible FXR antagonist (IC50 = 40 μM). Tauro-β-muricholic acid has antiapoptotic effect. Tauro-β-muricholic acid inhibits bile acid-induced hepatocellular apoptosis by maintaining the mitochondrial membrane potential[1][2]. |
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| Related Catalog | |
| Target |
40 μM (FXR)[1] |
| References |
| Molecular Formula | C26H45NO7S |
|---|---|
| Molecular Weight | 515.70300 |
| Exact Mass | 515.29200 |
| PSA | 152.54000 |
| LogP | 3.83980 |
| Tauro-β-muricholic Acid |
| Tauro-Beta-muricholic Acid |