Penicillin V Potassium-d5

Modify Date: 2023-04-25 10:38:38

Penicillin V Potassium-d5 Structure
Penicillin V Potassium-d5 structure
Common Name Penicillin V Potassium-d5
CAS Number 2699607-22-0 Molecular Weight 394.52
Density N/A Boiling Point N/A
Molecular Formula C16H13D5KN2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Penicillin V Potassium-d5


Penicillin V (Potassium)-d5 is the deuterium labeled Penicillin V Potassium[1]. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis[2][3][4][5].

 Names

Name Penicillin V Potassium-d5

 Penicillin V Potassium-d5 Biological Activity

Description Penicillin V (Potassium)-d5 is the deuterium labeled Penicillin V Potassium[1]. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis[2][3][4][5].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Sabath LD. Et, al. Phenoxymethylpenicillin (penicillin V) and phenethicillin. Med Clin North Am. 1970 Sep;54(5):1101-11.  

[3]. Kamme C, et, al. In vitro effect on group A streptococci of loracarbef versus cefadroxil, cefaclor and penicillin V. Scand J Infect Dis. 199325(1):37-42.  

[4]. Norén T, et, al. In vitro susceptibility to 17 antimicrobials of clinical Clostridium difficile isolates collected in 1993-2007 in Sweden. Clin Microbiol Infect. 2010 Aug16(8):1104-10.  

[5]. Overbosch D, et, al. Comparative pharmacodynamics and clinical pharmacokinetics of phenoxymethylpenicillin and pheneticillin. Br J Clin Pharmacol. 1985 May19(5):657-68.  

[6]. Hermansson A, et, al. Prevention of experimental acute otitis media with penicillin V. Acta Otolaryngol. Jan-Feb 1990109(1-2):119-23.  

 Chemical & Physical Properties

Molecular Formula C16H13D5KN2O5S
Molecular Weight 394.52