Penicillin V potassium

Modify Date: 2024-01-01 20:07:09

Penicillin V potassium structure	Common Name	Penicillin V potassium
	CAS Number	132-98-9	Molecular Weight	388.480
	Density	1.40	Boiling Point	681.4ºC at 760 mmHg
	Molecular Formula	C₁₆H₁₇KN₂O₅S	Melting Point	197-202°C
	MSDS	Chinese USA	Flash Point	365.9ºC
	Symbol	GHS07, GHS08	Signal Word	Danger

Use of Penicillin V potassium

Penicillin V Potassium is an antibiotic useful for the treatment of a number of bacterial infections, is a penicillin that is orally active, acts by inhibiting the biosynthesis of cell-wall peptidoglycan.

Name	phenoxymethylpenicillin potassium
Synonym	More Synonyms

Description	Penicillin V Potassium is an antibiotic useful for the treatment of a number of bacterial infections, is a penicillin that is orally active, acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Natural Products >> Others Research Areas >> Infection

Density	1.40
Boiling Point	681.4ºC at 760 mmHg
Melting Point	197-202°C
Molecular Formula	C₁₆H₁₇KN₂O₅S
Molecular Weight	388.480
Flash Point	365.9ºC
Exact Mass	388.049530
PSA	124.07000
Vapour Pressure	1.69E-19mmHg at 25°C
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH9275000

CHEMICAL NAME :: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxy- acetamido)-, monopotassium salt

CAS REGISTRY NUMBER :: 132-98-9

LAST UPDATED :: 199707

DATA ITEMS CITED :: 17

MOLECULAR FORMULA :: C16-H17-N2-O5-S.K

MOLECULAR WEIGHT :: 388.51

WISWESSER LINE NOTATION :: T45 ANV ESTJ CMV1OR& F1 F1 GVQ &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1040 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1124 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1351 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 195 gm/kg/13W-I

TOXIC EFFECTS :: Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16250 mg/kg/13W-I

TOXIC EFFECTS :: Gastrointestinal - other changes

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 500 mg/L

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-336,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82270 No. of Facilities: 1844 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3026 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82270 No. of Facilities: 301 (estimated) No. of Industries: 2 No. of Occupations: 11 No. of Employees: 6483 (estimated) No. of Female Employees: 3052 (estimated)

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H302-H317-H334
Precautionary Statements	P261-P280-P284-P301 + P312 + P330-P304 + P340-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R42/43
Safety Phrases	S22-S26-S36/37-S45
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XH9275000
HS Code	2941109400

6-Aminopenicill...

CAS#:551-16-6

Penicillin V po...

CAS#:132-98-9

Literature: WO2014/71283 A1, ;

Phenoxyacetyl c...

CAS#:701-99-5

Penicillin V po...

CAS#:132-98-9

Literature: WO2014/71283 A1, ;

Precursor 2
CAS#:551-16-6 6-Aminopenicill... CAS#:701-99-5 Phenoxyacetyl c...
DownStream 2
CAS#:52-67-5 D-penicillamine CAS#:2315-05-1 methyl 3,3-dime...

HS Code	2941109400

Fast determination of antibiotics in whole blood.

Clin. Microbiol. Infect. 19(9) , 869-74, (2013)

There is a need for analytical methods capable of monitoring blood antibiotic levels in real time. Here we present a method for quantifying antibiotic levels in whole blood that does not require any s...

(2S,5R,6R)-3,3-diméthyl-7-oxo-6-[(phénoxyacétyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate de potassium

D-a-Phenoxymethylpenicillinate K Salt

EINECS 205-086-5

[2S-(2a,5a,6b)]-3,3-Dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Potassium Salt

Penicillin V potassium

MFCD00051771

Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt

Potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Penicillin V Potassium Salt

Phenoxymethylpenicillin Potassium

4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, monopotassium salt, (2S,5R,6R)-

pen-oral

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((phenoxyacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid Monopotassium Salt

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, potassium salt, (2S,5R,6R)- (1:1)

Penicillin V (Potassium)

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Penicillin V potassium
Price: ￥148.0/100mg ￥168.0/5g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Penicillin V potassium
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Penicillin V potassium salt
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Penicillin V potassium
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: phenoxymethylpenicillin potassium
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Penicillin V potassium

Use of Penicillin V potassium

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