66648-50-8

66648-50-8 structure

Name: Ethyl caffeate
Chemical Name: ethyl 3,4-dihydroxycinnamate
CAS Number: 66648-50-8
Molecular Formula: C₁₁H₁₂O₄
Molecular Weight: 208.211
Catalog: Natural product Phenylpropanoid
Create Date: 2018-02-27 08:00:00
Modify Date: 2024-01-11 21:35:39
Ethyl trans-caffeate is the trans form of Ethyl Caffeate (HY-N6966). Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].

Name	ethyl 3,4-dihydroxycinnamate
Synonyms	Ethyl caffeate MFCD00045754 caffeic acid ethyl ester 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester ethyl caffeoate Ethyl 3-(3,4-dihydroxyphenyl)acrylate E-Caffeic acid ethyl ester

Description	Ethyl trans-caffeate is the trans form of Ethyl Caffeate (HY-N6966). Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.