Name | (E)-roxithromycin |
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Synonyms |
Roxid
Overal Forilin MFCD00214389 Roxithromycin Claramid biaxsig RU 965 Assoral roxyithromycin Brilid (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2-methoxyethoxy)methoxy]imino}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one Rulid Surlid |
Description | Roxithromycin is a semi-synthetic macrolide antibiotic.Target: AntibacterialRoxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. From Wikipedia. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 864.7±75.0 °C at 760 mmHg |
Melting Point | 115- 120ºC |
Molecular Formula | C41H76N2O15 |
Molecular Weight | 837.047 |
Flash Point | 476.7±37.1 °C |
Exact Mass | 836.524597 |
PSA | 216.89000 |
LogP | 3.73 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.535 |
Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
![]() GHS07 |
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Signal Word | Warning |
Hazard Statements | H302 |
Precautionary Statements | P301 + P312 + P330 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful |
Risk Phrases | R22 |
Safety Phrases | 26 |
RIDADR | NONH for all modes of transport |
RTECS | KF4990000 |
HS Code | 2941500000 |
~% 80214-83-1 |
Literature: EP1435359 A1, ; Page 5 ; |
Precursor 2 | |
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DownStream 0 |
HS Code | 2941500000 |
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