Roxithromycin
Modify Date: 2024-01-02 18:00:29
Roxithromycin structure
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Common Name | Roxithromycin | ||
|---|---|---|---|---|
| CAS Number | 80214-83-1 | Molecular Weight | 837.047 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 864.7±75.0 °C at 760 mmHg | |
| Molecular Formula | C41H76N2O15 | Melting Point | 115- 120ºC | |
| MSDS | Chinese USA | Flash Point | 476.7±37.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of RoxithromycinRoxithromycin is a semi-synthetic macrolide antibiotic.Target: AntibacterialRoxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. From Wikipedia. |
| Name | (E)-roxithromycin |
|---|---|
| Synonym | More Synonyms |
| Description | Roxithromycin is a semi-synthetic macrolide antibiotic.Target: AntibacterialRoxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. From Wikipedia. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 864.7±75.0 °C at 760 mmHg |
| Melting Point | 115- 120ºC |
| Molecular Formula | C41H76N2O15 |
| Molecular Weight | 837.047 |
| Flash Point | 476.7±37.1 °C |
| Exact Mass | 836.524597 |
| PSA | 216.89000 |
| LogP | 3.73 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.535 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| RTECS | KF4990000 |
| HS Code | 2941500000 |
|
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Roxithromycin CAS#:80214-83-1 |
| Literature: EP1435359 A1, ; Page 5 ; |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2941500000 |
|---|
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Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.
BMC Biol. 13 , 52, (2015) Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibitory compounds, making it an attractive target for antimalarial development. However... |
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A comparison of in vitro ADME properties and pharmacokinetics of azithromycin and selected 15-membered ring macrolides in rodents.
Eur. J. Drug Metab. Pharmacokinet. 39(4) , 263-76, (2014) The purpose of this study was to evaluate the impact of structural modifications on the 15-membered macrolactone ring and/or substituents on the in vitro ADME properties and in vivo pharmacokinetic (P... |
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Stability of dicyclohexylamine and fumagillin in honey.
Food Chem. 179 , 152-8, (2015) Fumagillin is extensively used to control nosema disease in apiculture. In the commercial formulation, fumagillin is present as a salt in an equimolar quantity with dicyclohexylamine (DCH). In this st... |
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- Shanghai Jizhi Biochemical Technology Co., Ltd
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- Product Name: Roxithromycin
- Price: ￥88.0/5g ￥88.0/200mg
- Purity: 98.0%
- Stocking Period: 2 Day
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Roxithromycin
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- Purity: 98.0%
- Stocking Period: Inquiry
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- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Roxithromycin
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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