Name | disodium,(4-nitrophenyl) phosphate,hexahydrate |
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Synonyms |
MFCD00066288
di-Sodium 4-nitrophenyl phosphate pNPP disodium salt hexahydrate DisodiuM 4-Nitrophenylphosphate Hexahydrate Phosphoric Acid 4-Nitrophenyl Ester Disodium Salt Hexahydrate Phosphatase substrate 4-Nitrophenyl Phosphate,Disodium Salt Hexahydrate p-Nitrophenyl phosphate disodium hexahydrate pNPP disodium hexahydrate 4-Nitrophenyl phosphate disodium salt hexahydrate p-Nitrophenyl phosphate disodium hexahydrate,Disodium 4-nitrophenyl phosphate hexahydrate,di Sodium 4-nitrophenyl phosphate hexahydrate EINECS 224-246-5 Disodium 4-Nitrophenyl Phosphate Hexahydrate |
Description | 4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm[1]. |
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Related Catalog | |
In Vitro | 4-Nitrophenyl phosphate (PNPP) disodium hexahydrate is a commonly used substrate for alkaline phosphatases (ALPs). 4-Nitrophenyl phosphate disodium hexahydrate is hydrolyzed by ALP to PNP (p-nitrophenol), which quenches the fluorescence of novel gold nanoclusters (AuNCs) by the inner filter effect (IFE)[2]. |
References |
Boiling Point | 457.8ºC at 760mmHg |
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Melting Point | >300ºC(lit.) |
Molecular Formula | C6H16NNa2O12P |
Molecular Weight | 371.14400 |
Flash Point | 230.7ºC |
Exact Mass | 371.02100 |
PSA | 183.43000 |
LogP | 2.08010 |
Appearance | tablets | white to pale yellow |
Storage condition | 2-8°C |
Water Solubility | H2O: 25 mg/mL at 20 °C, clear, yellow-green |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Safety Phrases | 24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |