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23981-47-7

23981-47-7 structure
23981-47-7 structure
  • Name: 2-(6-Methoxynaphthalen-2-yl)acetic acid
  • Chemical Name: (6-methoxy-2-naphthyl)acetic acid
  • CAS Number: 23981-47-7
  • Molecular Formula: C13H12O3
  • Molecular Weight: 216.233
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-07-30 14:47:18
  • Modify Date: 2024-01-03 09:10:46
  • α-Demethylnaproxen is the major metabolite of Nabumetone (HY-B0559), Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity[1][2].

Name (6-methoxy-2-naphthyl)acetic acid
Synonyms (6-Methoxy-2-naphthyl)acetic acid
(6-methoxynaphthalen-2-yl)acetic acid
2-Naphthaleneacetic acid, 6-methoxy-
6-Methoxy-2-naphthaleneacetic Acid
2-(6-methoxynaphthalen-2-yl)acetic acid
Description α-Demethylnaproxen is the major metabolite of Nabumetone (HY-B0559), Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity[1][2].
Related Catalog
Density 1.2±0.1 g/cm3
Boiling Point 408.8±20.0 °C at 760 mmHg
Melting Point 171-173ºC
Molecular Formula C13H12O3
Molecular Weight 216.233
Flash Point 160.7±15.3 °C
Exact Mass 216.078644
PSA 46.53000
LogP 2.65
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.625

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ1045000
CHEMICAL NAME :
2-Naphthaleneacetic acid, 6-methoxy-
CAS REGISTRY NUMBER :
23981-47-7
BEILSTEIN REFERENCE NO. :
2371586
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H12-O3
MOLECULAR WEIGHT :
216.25
WISWESSER LINE NOTATION :
L66J CO1 H1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 119,600,1980
Hazard Codes Xi
HS Code 2918990090
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%