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76948-72-6

76948-72-6 structure
76948-72-6 structure
  • Name: Cleomiscosin A
  • Chemical Name: cleomiscosin A
  • CAS Number: 76948-72-6
  • Molecular Formula: C20H18O8
  • Molecular Weight: 386.352
  • Catalog: Natural product Lignans
  • Create Date: 2018-06-18 14:58:24
  • Modify Date: 2025-08-20 16:09:20
  • Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages[1][2].

Name cleomiscosin A
Synonyms Cleomiscosin A
(2R,3R)-3-(4-Hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one
9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one, 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-, (2R,3R)-
Description Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages[1][2].
Related Catalog
Target

TNF-α

References

[1]. Sharma S, et al. Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Eur J Med Chem. 2010;45(11):5150-5156.

[2]. Ma M, et al. Zhongguo Zhong Yao Za Zhi. 2007;32(12):1175-1179.

Density 1.4±0.1 g/cm3
Boiling Point 632.7±55.0 °C at 760 mmHg
Melting Point 245-247ºC
Molecular Formula C20H18O8
Molecular Weight 386.352
Flash Point 228.5±25.0 °C
Exact Mass 386.100159
PSA 107.59000
LogP 1.44
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.618
Hazard Codes Xi
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