4105-38-8
4105-38-8 structure
- Name: uridine triacetate
- Chemical Name: 2',3',5'-Tri-O-acetyluridine
- CAS Number: 4105-38-8
- Molecular Formula: C15H18N2O9
- Molecular Weight: 370.311
- Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
- Create Date: 2018-09-16 10:49:26
- Modify Date: 2026-07-06 20:55:31
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Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2].
| Name | 2',3',5'-Tri-O-acetyluridine |
|---|---|
| Synonyms |
1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
Vistogard TAU Tri-O-acetyl uridine Mtapt UNII-2WP61F175M (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4 2`,3`,5`-Triacetyluridine URIDINE 2',3',5'-TRIACETATE EINECS 223-881-5 Uridine 2',3',5'-triacetate 2',3',5'-Tri-O-acetyluridine //BP 2’,3’,5’-Triacetyluridine 2`,3`,5`-Tracetyluridine ANTI-TAU (MAPT) (S720) antibody produced in rabbit 2',3',5'-Tri-O-acety DDPAC 2',3',5'-Tri0acetyluridine 1-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-4-hydroxypyrimidine-2(1H)-one 2',3',5'-Triacetyluridine Phospho-14-&theta [4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate Xuriden [(2S,3R,4S,5S)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyriMidin-1-yl)oxolan-2-yl]Methyl acetate 2',3',5'-trioacetyluridine MFCD00023795 Vistonuridine 2-[(acetyloxy)methyl]-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyri 2',3',5-TRI-ACETYLURIDINE 2',3',5'-Tri-O-acetyl-D-uridine Mouse Anti-Tau antibody 2',3',5'-Tri-O-acetyl-rU [4-acetyloxy-2-(acetyloxymethyl)-5-( Uridine, 2',3',5'-triacetate (2R,3R,4R,5R)-2-(AcetoxyMethyl)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate 2',3',5'-tri-O-Acetyluridine (HPLC) Microtubule-associated protein tau (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate Uridine triacetate, 10 mM in DMSO acetic acid [4-acetoxy-2-(acetoxymethyl)-5-(2,4-diketopyrimidin-1-yl)tetrahydrofuran-3-yl] ester FTDP-17 (Ser232) BioAssay&trade acetic acid [4-acetoxy-2-(acetoxymethyl)-5-(2,4-dioxo-1-pyrimidinyl)-3-tetrahydrofuranyl] ester 2'', 3'', 5''-TRIACETYLURIDINE (2'', 3'', 5''-TRI-O-ACETYLURIDINE) 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyrimid [(2R,3R,4R,5R)-4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] ethanoate phosphorylated (S232) ANTI-TAU(C-TERMINAL) antibody produced in rabbit [4-acetoxy-2-(acetoxymethyl)-5-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-3-yl] acetate MAPTL PPP1R103 2-(acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate Uridine triacetate acetic acid [(2R,3R,4R,5R)-4-acetoxy-2-(acetoxymethyl)-5-(2,4-diketopyrimidin-1-yl)tetrahydrofuran-3-yl] ester O2',O3',O5'-triacetyl-uridine 2',3',5'-TriacetyL MTBT1 2',3',5'-O-triacetyluridine MTBT2 [(2R,3R,4R,5R)-4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate |
| Description | Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2]. |
|---|---|
| Related Catalog | |
| References |
[2]. Cada DJ, et al. Uridine Triacetate. Hosp Pharm. 2016 Jun;51(6):484-8. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Melting Point | 124-134ºC |
| Molecular Formula | C15H18N2O9 |
| Molecular Weight | 370.311 |
| Exact Mass | 370.101227 |
| PSA | 142.99000 |
| LogP | -0.11 |
| Index of Refraction | 1.552 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| Precursor 7 | |
|---|---|
| DownStream 10 | |
